Prescription drugs in spotlight after Jackson death

LOS ANGELES (AFP) – Michael Jackson’s death has lifted a veil on the sinister underbelly of fame, with associates of the pop icon hitting out at celebrity-dazzled doctors who funnel powerful narcotics to the stars.

Jackson, who died Thursday aged 50 after collapsing at his home in Beverly Hills, had a long history of prescription drug use, stretching back to 1993 when allegations of child abuse were leveled against him.

Reports that Jackson had been injected with a powerful painkiller by a personal physician shortly before his death triggered speculation that the star had a ready supply of prescription medications.

According to Jackson’s close friend and confidante, new age guru and trained cardiologist Deepak Chopra, the entertainment world is rife with doctors who trade their access to drugs for celebrity.

“There’s a plethora of doctors in Hollywood that are drug peddlers, they are drug pushers,” Chopra told CNN. “They just happen to have a medical license.”

Chopra spoke of a “huge problem” Hollywood had with “celebrity doctors who not only initiate people into the drug experience but then they perpetuate it so that people become dependent on them.

“I think this is something that really should be investigated because it’s a disease,” Chopra added.

“The number-one cause of drug addiction in the world, and particularly in the United States, is not street drugs but medical prescriptions given legally by physicians.”

The fatal alliance of drugs and celebrity has been one of Hollywood’s longest-running narratives, whether the decades-long addiction battle fought by Judy Garland before her death in 1969 aged 47 or recent cases, such as the accidental overdose of Australian actor Heath Ledger in New York in 2008.

The circumstances surrounding Jackson’s demise have meanwhile evoked eerie comparisons with the 2007 death of former Playboy model Anna Nicole Smith.

Smith died of an accidental drug overdose in a hotel in Florida. An autopsy subsequently found a lethal cocktail of several prescription drugs in her body.

Her boyfriend and two doctors are currently facing trial in California, accused of conspiring to provide the platinum blonde sex symbol with prescription drugs.

“These individuals repeatedly and excessively furnished thousands of prescription pills to Anna Nicole Smith, often for no legitimate medical purpose,” California Attorney General Edmund Brown said in March.

The US Drug Enforcement Administration on Friday renewed concerns about rising deaths from misuse of prescription pills.

“Diversion and abuse of prescription drugs are a threat to our public health and safety similar to the threat posed by illicit drugs such as heroin and cocaine,” said Gil Kerlikowske, director of national drug control policy.

Chopra meanwhile revealed he first had an inkling Jackson was receiving drugs from multiple sources following his 2005 acquittal on child-sex charges when the star had stayed at his home.

“At one point, he started asking me for a prescription. He knew I was a physician. I had a license. He asked me for a prescription for a narcotic. And I said what the heck do you want a narcotic prescription for?” Chopra said.

“It suddenly dawned on me that he was already taking these and that he had probably a number of doctors who were giving him these prescriptions.”

Chopra’s concerns appeared to be supported by the former nanny of Jackson’s three children, Grace Rwaramba, who was quoted in British newspapers on Sunday as saying she regularly had to pump the star’s stomach.

The star was addicted to narcotic painkillers, she said in comments reported by The Sunday Times.

“I had to pump his stomach many times. He always mixed so much of it,” said Rwaramba, 42.

“There was one period that it was so bad that I didn’t let the children see him… He always ate too little and mixed too much.”

 

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New Drug Shows Promise for Rheumatoid Arthriitis

FRIDAY, June 26 (HealthDay News) — A new drug to treat rheumatoid arthritis reduces joint inflammation in severe cases while causing only mild to moderate side effects, according to a report from the first clinical trial of the drug on humans.

Masitinib, which is being developed by AB Science pharmaceuticals, is supposed to halt the activity of mast cells, a part of the immune system believed to be involved in the start and progression of rheumatoid arthritis.

The results of the French trial, involving 43 people with arthritis that other treatments had failed to help, appears online in Arthritis Research and Therapy.

“We are encouraged from this study that masitinib not only appears to be effective, but that within the first three months of treatment, the worst of its side effects were over, possibly making it suitable for long-term treatment regimens,” one of the researchers, Olivier Hermine, said in a news release from the journal’s publisher. The next step will be placebo-controlled trials, he added.

 

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Viagra sold at local chemists

LONDON (AFP) – Men will be able to buy Viagra on the High Street for the first time instead of going to a doctor after Boots launched a nationwide scheme on Friday.

Stores across the country will sell the erectile dysfunction drugs to men after they undergo a private half-hour consultation with a pharmacist.

Pharmacists will conduct a pre-screening questionnaire, take a medical history and conduct a series of blood tests, including checking glucose, blood pressure and cholesterol levels to rule out a more serious health problem.

The scheme follows a trial at Boots stores in Manchester.

Pharmacist James Longden, who led the trial, said men had travelled from around the country to buy the small blue pills.

“We had men coming not just from the North West but from all over.

“They were really positive about it. Sometimes it can be a bit of an embarrassing subject to talk about and many didn’t know where to turn to for help,” Longden said.

Costing 55 pounds for the initial screening and four tablets, the price will drop to 26.59 pounds for further supplies of four tablets.

Erectile dysfunction affects one in 10 men in Britain and it is estimated that only 10 percent of the estimated 2.3 million men who suffer are being treated.

But research by Boots has indicated that 47 percent of men would prefer to suffer in silence rather than discuss erection problems with anyone.

Patricia Lohr, medical director of the sexual healthcare charity BPAS, said women should also have the convenience of buying drugs from their chemist rather than seeing a doctor.

“It’s fine that men will be able to pick up Viagra alongside their shaving foam at their local pharmacist.

“But why can’t women access effective contraception by the same easy means? The contraceptive pill is safe, effective and used by millions of women worldwide - many more than men who use Viagra.

“A pharmacist can’t even provide a woman with a repeat prescription for the pill - she has to return to the doctor’s surgery time and again.”

 

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Novartis produces first batch of swine flu vaccine

BASEL, Switzerland (AFP) – Swiss drugs giant Novartis has completed a first batch of swine flu vaccine for pre-clinical trials and aims to make a version available in the fall, the company said.

“Novartis has successfully completed the production of the first batch of influenza A(H1N1) vaccine, weeks ahead of expectations,” the company said in a statement.

The 10-litre batch “will be used for pre-clinical evaluation and testing and is also being considered for use in clinical trials,” it said.

Novartis hopes to start clinical trials in July and “expects licensure in the fall of 2009,” it said.

It added that “more than 30 governments have made requests to Novartis to supply them with influenza A(H1N1) vaccine ingredients.”

The company used cell-based technology to produce the vaccine, a faster method than the traditional technology that uses eggs, according to Novartis.

Novartis received 289 million dollars (206.8 million euros) last month from the US Department of Health and Human Services for the development of the vaccine.

The World Health Organization declared a swine flu pandemic on Thursday, ratcheting up its alert to the maximum level of six.

Swine flu has infected people almost 30,000 people in 75 countries and claimed 144 lives since it was first detected in Mexico in April.

 

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